Learn about our world class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
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The measurement of protein phosphorylation is a useful tool for measuring the modulation of receptor activation by both antibodies and small molecules. CCR7 and CXCR2 receptors, which are expressed in immune cells and are therapeutic targets for disorders like lupus erythematosus, adult leukemia, lymphomas, chronic obstructive pulmonary disease (COPD), and sepsis.
AlphaLISA™ SureFire® Ultra™ and Alpha SureFire® Ultra™ Multiplex assays are automation-friendly, applicable to both small and large-scale screens, and can assess phosphorylation status in complex matrices. The LANCE Ultra cAMP assay is measures cyclic AMP (cAMP) produced upon modulation of adenylyl cyclase activity by G-protein coupled receptors (GPCRs).
This application note demonstrates how the SureFire Ultra and LANCE Ultra cAMP assays can be used for measuring inhibitors to CCR7 and CXCR2 cell surface receptors using a cellular model system where these receptors are overexpressed in CHO cells. The assays were optimized to measure receptor blockage and assayed receptor activity modulation by detecting ERK and AKT phosphorylation status and cAMP modulation. For more details, download the application note!
For research use only. Not for use in diagnostic procedures.
Characterizing chemokine receptor inhibitors with AlphaLISA SureFire Ultra, Alpha SureFire Ultra Multiplex and LANCE Ultra cAMP assays