Streamlining multi-sample tissue homogenization and sonication for epigenetic applications

Epigenetics is a crucial part of multiomics research and drives our understanding of regulatory mechanisms in biological processes, offering diverse applicability for therapeutic discovery, lifestyle interventions, biomarker identification, and other areas of research. Our process optimization webinar features benchtop solutions for multi-sample homogenization and sonication upstream NGS-based epigenetic techniques, helping researchers standardize assay workflows for improving analytical reproducibility from precious samples at the bench. The webinar ends with an open Q&A.

Key highlights:

• Optimized protocol and data review for multi-sample human and mouse tissue processing, such as for ChIP-seq
• Leveraging automated repeatability strategies when scaling throughput while preserving sample quantity and integrity via multi-sample sonication and bead mill homogenization.
• Dive into cutting-edge NGS-based lab techniques, starting from ChIP-Seq, to ATAC-Seq, through CUT&RUN, and how to apply them to answer different questions, along with a high-level overview into workflow QCs and bioinformatics including identifying library profiles and understanding your FASTQ files, peak calling, and motif analysis

Speakers:

• Dr. Rwik Sen, PhD – Sr. FAS and Product Group Leader, Active Motif®
• Gabriella Ryan, M.S. - Senior Application Scientist, Omni portfolio, Revvity

For research use only. Not for use in diagnostic procedures.