The AlphaLISA™ SureFire® Ultra™ Total CHK2 assay is a sandwich immunoassay for quantitative detection of total CHK2 in cellular lysates using Alpha Technology.
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Total CHK2 assay is a sandwich immunoassay for quantitative detection of total CHK2 in cellular lysates using Alpha Technology.
Checkpoint kinase 2 (CHK2) is a serine-threonine kinase and an integral member of the signaling cascade that controls the G1 cell cycle checkpoint. CHK2 is activated in response to DNA double-strand breaks and phosphorylates several modulators of cell cycle control including tumor suppressor proteins and prevents unchecked cell division. Mutations in CHK2 are linked to a wide range of cancers, such as breast, lung, prostate, kidney, and thyroid.
The AlphaLISA SureFire Ultra Total CHK2 assay is a sandwich immunoassay for the quantitative detection of Total CHK2 in cellular lysates, using Alpha Technology.
Formats:
AlphaLISA SureFire Ultra kits are compatible with:
Alpha SureFire kits can be used for:
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Lysis Buffer Compatibility |
Lysis Buffer
|
Molecular Modification |
Total
|
Product Group |
Kit
|
Sample Volume |
10 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
CHK2
|
Target Class |
Phosphoproteins
|
Target Species |
Human
|
Technology |
Alpha
|
Therapeutic Area |
Oncology
|
Unit Size |
50,000 assay points
|
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