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Guanosine 3',5'-Cyclic Phosphate, Ammonium Salt, [8-3H-]-, 250 µCi (9.25 MBq)

cGMP, tritiated at C8. Tritiated cGMP is commonly used in phosphodiesterase (PDE) assays.

Feature Specification
Concentration 1 mCi/mL
Label Position Specifically Labeled
Molecular Weight 362.3

cGMP, tritiated at C8. Tritiated cGMP is commonly used in phosphodiesterase (PDE) assays.

Product Variants
Unit Size: 250 µCi
Part #:
NET337250UC
List Price
USD 1,906.00
Unit Size: 1 mCi
Part #:
NET337001MC
List Price
USD 3,861.90
For research use only. Not for use in diagnostic procedures.
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Overview

250 µCi quantities of Guanosine 3',5'-Cyclic Phosphate, Ammonium Salt, [8-3H]-, are available for your research. Radiochemical Purity is >96%

250 µCi quantities of [8-3H]-Guanosine 3',5'-Cyclic Phosphate (cGMP), Ammonium Salt, are available for your research. Application of [3H]cGMP can be found in: binding domains of a specific phosphodiesterase in cellular signalling, interactions of mefloquine with ABC proteins (MRP1 and MRP4) in biochemical pharmacology, expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5) in pharmacology, etc.

Special Information:

  • CONVERSION TO OTHER SALTS: The ammonium salt may be converted to that of another cation by passing it through a small column of exchange resin in the form the desired cation. A 1-2mL quantity of thoroughly washed resin is generally satisfactory. Necessary precautions should be exercised to minimize any breakdown from occurring during this procedure.
  • Removal of Solvent: An aliquot or the entire sample can be taken to dryness by directing a gentle stream of inert gas (nitrogen) over the surface of the solution. The temperature of the solution should not be allowed to exceed 20°C during the drying process, and the compound should not be permitted to remain in the solid state any longer than necessary.

Specifications

Concentration
1 mCi/mL
Molecular Weight
362.3
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
Ethanol : water (1:1)
Detection Modality
Radiometric
Label Position
Specifically Labeled
Packaging
NENSure vial
Radioisotope
3H
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
-20°C
Unit Size
250 µCi

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