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Application Note
Phenotype discrimination using the PhenoVue cell painting and multi-organelle staining kits
In this study, we analyzed the phenotypes induced by a set of 15 reference compounds using both the PhenoVue cell painting kit and the PhenoVue multi-organelle staining kit to compare phenotypic discrimination results of the two assays.
FAQ
Cell painting: your questions answered
Your cell painting questions are answered by Revvity's experts in this FAQ article, providing guidance and best practices for cell painting assays.
Infographic
Cell painting: from images to innovation
Learn everything you need to know about cell painting, including what it is, how it works, and what you need to get started.
Whitepaper
Cell painting - a cellular imaging and machine learning approach to drug discovery
Cell painting solutions from Revvity offer powerful phenotypic high-content screening methods that help to accelerate drug discovery by delivering more predictive data.
Application Note
Cell painting for phenotypic screening
Application note describing how to set-up a cell painting assay.
Technical Note
Automated high-content assay using GrowDex-embedded spheroids dispensed on JANUS G3 automated liquid handling workstation
Improve throughput as well as assay statistics by automating the liquid handling steps of a 384-well, hydrogel-based high-content toxicity assay
Application Note
Orthogonal validation of CRISPRCas9 and siRNA generated phenotypes using cell painting
Investigate cell cycle regulation through AURKB, GMNN, and PLK1 proteins. Learn how CRISPR-Cas9 and siRNA techniques, combined with high-content imaging on the Opera Phenix™ Plus, reveal their roles in cell division and genomic stability.
Application Note
Evaluation of drug selectivity and efficacy using PROTACs in a 3D co-culture spheroid model
The aim of this study was to evaluate the efficacy and selectivity of SJF1528, a pan-EGFR PROTAC, and MS39, a mutant-specific EGFR L858R PROTAC, while exploring the use of both high-content imaging and no-wash HTRF immunoassays in encapsulated 3D spheroid models.
Flyer
Cell line development solutions flyer
Optimize your biotherapeutic development with our CHOSOURCE™ platform for cell line development workflows
Guide
Guide to reducing the cost and time to set-up reproducible HTS/HCS with 3D cell models
Download our guide to reducing the costs and time required to set up reproducible high-throughput and high-content screens using 3D cell culture models.
Guide
How to transfer from animal-derived matrices to GrowDex - 3D cell culture matrix
Guide to transferring 3D cell culture to GrowDex hydrogel from animal-derived matrices.
Application Note
Evaluating HTRF and AlphaLISA SureFire Ultra detection methods in GrowDex-supported 3D MCF7 cell cultures
Application note describing the evaluation of HTRF and AlphaLISA SureFire Ultra detection methods in GrowDex-supported 3D MCF7 cell cultures.
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