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Application Note
Proinflammatory cytokine evaluation from human PBMCs in response to AAV8 peptides
This application note discusses the evaluation of proinflammatory cytokines from human PBMCs in response to AAV8 peptides using HTRF and ELISpot technologies. It highlights the methodology, results, and significance of cytokine profiling in the context of gene therapy.
Whitepaper
Addressing the challenges of bispecific antibody characterization with high-throughput platforms
With the complexities of bispecific antibody development and characterization explore the binding assays and technology through real-world examples
Product Note
Automated characterization of proteins and nucleic acids
Streamline your slab gel electrophoresis, while providing increased throughput and the data formats required for biotherapeutics and genomics workflows.
Whitepaper
Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.
Application Note
Characterization of NISTmAb with microfluidic CE-SDS
Application note demonstrating NISTmAb characterization using capillary electrophoresis on the LabChip GXII Touch Protein Characterization System.
Application Note
An evaluation of control analysis system performance between the LabChip GXII and SCIEX PA800 Plus system
In this app note mAbs were evaluated using the Protein Clear™ HR assay and an orthogonal method, the SCIEX® PA800 Plus system.
Technical Note
Quantifying TNFR1 in both soluble and membrane bound form using AlphaLISA technology
Quantifying TNFR1 in both soluble and membrane bound form using AlphaLISA technology
Technical Note
Quantitative analysis of lysine 36 demethylation with AlphaLISA
This technical note provides details on how the AlphaLISA immunodetection assay quantifies the demethylation of a biotinylated Histone H3 (21-44) peptide that is tri-methylated at lysine 36
Technical Note
AlphaLISA Acetyl‑Histone H3 lysine 9 (H3K9ac) cellular assay
This technical note provides information on how the AlphaLISA immunodetection assay detects variations in acetylated histone H3 lysine 9 (H3K9ac) levels within cellular extracts
Technical Note
Assessing AST released in a cell culture model of liver toxicity using AlphaLISA
In this technical note, we showcase the utility and advantages of using AlphaLISA assays to identify and quantify AST protein levels in cellular lysate and supernatant from a human hepatoma cell line
Technical Note
AlphaLISA for biomarkers in urine: Measuring the renal tubular injury indicator, β2-microglobulin
In this study, AlphaLISA™ technology is demonstrated for the first time in the complex matrix of urine, and is shown to detect the renal tubular injury marker Beta2-microglobulin (β2-microglobulin), in urine at a sensitivity
Whitepaper
Achieving higher throughput for the bioanalysis of advanced biotherapeutics
With advanced biotherapeutics requiring characterization and stringent quality control, read how by assessing critical quality attributes early within cell line development you can improve your chances in clinic
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