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Case Study
Re-tooling anti-microbial research for the 21st century
Case study describing the analysis of bacterial phenotypes to investigate adaptive mechanisms of antimicrobial resistance and screening for novel alternatives.
Whitepaper
Artificial intelligence, machine learning and deep learning: applications in cellular imaging for improved drug discovery productivity
Learn how Artificial Intelligence (AI), Machine Learning (ML) and Deep Learning (DL) are used in cellular imaging applications for improved drug discovery productivity in this white paper.
Whitepaper
Phenotypic drug discovery with high content screening
High content screening, a powerful approach to phenotypic drug discovery that leverages the rich information available in the image-based screens.
Technical Note
The benefits of water immersion lenses for high-content screening
This technical note explains why the choice of objective lens is critical for high-content screening.
Technical Note
Opera Phenix Plus high-content screening system: crosstalk suppression
Technical note describing how fluorescent crosstalk is suppressed by the Opera Phenix Plus high-content screening system.
Technical Note
Improved high-content imaging of tissue sections
Technical note describing how to improve high-content imaging of tissue sections.
Application Note
Distinguishing cell types by phenotypic profiling of the nucleus
As nearly all screening approaches require a nuclear counterstain, phenotypic profiling of the nuclei can offer new insights on assays at no extra cost.
Literature - Publication Review
Organ-on-chips: increased complexity for higher physiological relevance in pharmaceutical safety testing
Explore the advancements of liver and kidney-on-chip models, and how these platforms effectively simulate toxicity responses.
Literature - Publication Review
Morphological profiling of human T and NK lymphocytes by high-content imaging
The study in this publication review provides a foundation for the development of morphological profiling as a scalable approach to monitor the immune synapse (IS), primary lymphocyte responsiveness and microarchitecture.
Technical Note
3D volumetric analysis of luminal spaces inside cysts or organoids
Technical Note describing 3D volumetric analysis of luminal spaces inside cysts or organoids
Literature - Publication Review
Multifunctional mRNA-based CAR T-cells show promising anti-tumor activity against glioblastoma
Learn how researchers have evaluated the efficiency of mRNA-based multifunctional CAR T-cells against glioblastoma in vitro and in vivo.
Application Note
Fast Kinetic Calcium Flux Imaging Using the Opera Phenix Plus High-Content Screening System
Application Note - Fast Kinetic Calcium Flux Imaging Using the Opera Phenix Plus High-Content Screening System.
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