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Artemisinins target GABAA receptor signaling and impair α cell identity
Artemisinins Target GABA Receptor Signaling and Impair α Cell Identity encouraging α cells to convert into insulin-producing β-like cells.

High-content analysis of drug-induced oligodendrocyte differentiation promoting remyelination in multiple sclerosis
Case study describing High-Content Analysis of Drug-Induced Oligodendrocyte Differentiation Promoting Remyelination in Multiple Sclerosis

A multiparametric live-cell cytotoxicity analysis using the Operetta High-content Analysis System
An in vitro cytotoxicity approach using HepG2 cells, which are used as an effective indicator of the human hepatotoxicity potential of test compounds.

Analyzing ERK signal transduction in live cells using a FRET-based biosensor
Application note describing analysis of ERK signal transduction in live cells using a FRET-based biosensor with the Operetta CLS high-content analysis system.

B cell selection and therapeutic antibody characterization using the Operetta high content imaging system
This case study illustrates how Revvity’s high content imaging solutions are enabling therapeutic antibody development.

Advanced characterization tools for organoid research: Analyzing cell type diversity, morphology, and function
Literature review highlighting advancements in organoid characterization techniques for analyzing cell type diversity, morphology, and function.

Addressing the challenges of bispecific antibody characterization with high-throughput platforms
With the complexities of bispecific antibody development and characterization explore the binding assays and technology through real-world examples

Quantifying TNFR1 in both soluble and membrane bound form using AlphaLISA technology
Quantifying TNFR1 in both soluble and membrane bound form using AlphaLISA technology

Quantitative analysis of lysine 36 demethylation with AlphaLISA
This technical note provides details on how the AlphaLISA immunodetection assay quantifies the demethylation of a biotinylated Histone H3 (21-44) peptide that is tri-methylated at lysine 36

High-content imaging of brain-on-chip microfluidic devices using PreciScan intelligent acquisition.
In collaboration with ETAP-Lab, this technical note demonstrates automated image acquisition of brain-on-chip microfluidic devices for neuronal research.

Unlocking the potential of cancer immunotherapy: Overcoming the challenges of 3D immune cell killing assays
Explore several successful assay setups that utilize various analysis technologies to study the antitumor functions of immunotherapies in a 3D environment.

Label-free analysis of cardiomyocyte beating using the Opera Phenix Plus System
Learn how to reliable quantify cardiomyocyte beating frequency using the Opera Phenix Plus high-content screening system in this application note.


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