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Application Note
HTRF phospho-total lysis buffer: a universal alternative to RIPA lysis buffers
This application note compares the use of Revvity’s HTRF phospho-total lysis buffer with commonly-used RIPA lysis buffers for the analysis of cell signaling pathways in different types of samples.
Literature - Publication Review
Fibrosis study investigating the role of GPCR signaling in fibrosis development
Discover publications on GPCR signaling pathways involved in fibrotic disorders.
Application Note
A simple, reliable, no-wash assay platform for AAV capsid titer quantification based on HTRF technology
In this application note you will discover a reliable and efficient method for quantifying AAV titers for AAV1, AAV2, AAV3B, AAV5, AAV6, AAV8, and AAV9 serotypes.
Literature - Publication Review
HTRF solutions for cytokines in autoimmune inflammation research
Discover publications using cytokine read-outs to screen drug targets in autoimmune diseases.
Guide
Get your insulin guide
This brochure describes the functionality and benefits of all 3 assay kits available for insulin quantification.
Literature - Publication Review
Tau aggregation in Alzheimer's disease pathogenesis addressed with HTRF assays
Literature review investigating mechanisms of the development of Alzheimer’s disease, tauopathies, and drug discovery efforts.
Literature - Publication Review
Monitoring CAR-T cells activation and their cytotoxicity
The publications highlighted demonstrate the capability of assay technologies to aid in the discovery of cell-based immunotherapies.
Application Note
Characterization of candidate molecules through GTP binding assays
Discover the characterization process for candidate molecules targeting Gα-protein activation through GPCRs with the functional HTRF® GTP binding assays.
Application Note
Determination of association and dissociation rates constants using the Tag-lite platform
The flexibility and throughput of the Tag-lite platform enables fast and easy calculation of the koff and kon constants for a given receptor.
Literature - Publication Review
Key signaling pathways in liquid cancer: therapeutic targets, screening tools, and future developments
This review highlights some of these signaling pathways and demonstrates how assays based on HTRF and AlphaLISA technologies can be used in the screening and development of new therapies for leukemia and lymphoma treatment.
Application Note
Best practices for analyzing tumor xenografts
This technical note provides procedures and guidelines for performing HTRF phospho-protein assays on tumor xenografts, with a particular focus on the preparation of tumor lysates and working samples.
Guide
Oncology guide: cellular signaling processes involved in cancer development and progression
Discover scientific background and illustrations covering cellular changes associated with many of the hallmarks of cancer.
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