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Application Note
HTRF phospho-total lysis buffer: a universal alternative to RIPA lysis buffers
This application note compares the use of Revvity’s HTRF phospho-total lysis buffer with commonly-used RIPA lysis buffers for the analysis of cell signaling pathways in different types of samples.
Guide
Benefit from a collection of important NAFLD pathways
Useful overview of today’s NAFLD knowledge
Literature - Publication Review
Fibrosis study investigating the role of GPCR signaling in fibrosis development
Discover publications on GPCR signaling pathways involved in fibrotic disorders.
Application Note
A simple, reliable, no-wash assay platform for AAV capsid titer quantification based on HTRF technology
In this application note you will discover a reliable and efficient method for quantifying AAV titers for AAV1, AAV2, AAV3B, AAV5, AAV6, AAV8, and AAV9 serotypes.
Guide
The ultimate guide to successful kinase binding experiments
This manual provides the kinase research community with the most up to date guidelines for the optimization of kinase assays.
Literature - Publication Review
HTRF solutions for cytokines in autoimmune inflammation research
Discover publications using cytokine read-outs to screen drug targets in autoimmune diseases.
Guide
Get your insulin guide
This brochure describes the functionality and benefits of all 3 assay kits available for insulin quantification.
Literature - Publication Review
Tau aggregation in Alzheimer's disease pathogenesis addressed with HTRF assays
Literature review investigating mechanisms of the development of Alzheimer’s disease, tauopathies, and drug discovery efforts.
Literature - Publication Review
Monitoring CAR-T cells activation and their cytotoxicity
The publications highlighted demonstrate the capability of assay technologies to aid in the discovery of cell-based immunotherapies.
Application Note
TCR phospho signaling investigation with HTRF
In this Note, we used HTRF phospho assays to study specific and ubiquitous proteins in the TCR pathway (ZAP70, SLP76, ERK …) in Peripheral Blood Mononuclear Cells (PBMC) and isolated T cells both under stimulation and in checkpoint inhibition conditions.
Application Note
Characterization of candidate molecules through GTP binding assays
Discover the characterization process for candidate molecules targeting Gα-protein activation through GPCRs with the functional HTRF® GTP binding assays.
Application Note
HTRF analysis and imaging of phospho-S65-ubiquitin in cellular models of mitophagy
Discover how to utilize a no-wash Phospho Ubiquitin Serine 65 immunoassay specifically for studying mitophagy activation.
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