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Application Note
Developing novel tetraubiquitin substrates and AlphaLISA technology to provide next generation deubiquitinase assays
This application note presents novel biochemical DUB assays that use TUBEs to bind to tetraubiquitin substrates of at least three natural linkages. These assays, combined with Revvity’s AlphaLISA™ technology, allow for the measurement of protein interactions and large protein complexes in a no-wash, homogeneous assay.
Application Note
Detection of human matrix metalloproteinase 9 in complex sample matrices, a comparison of AlphaLISA and colorimetric ELISA immunoassays
This note compares two immunoassay technologies: ELISA (enzyme-linked immunosorbent assay) and AlphaLISA™ (amplified luminescent proximity-based homogeneous assay).
Application Note
High-throughput DNA quantification for next generation sequencing on the VICTOR Nivo
In this application note, we compare the results of two dsDNA quantification methodologies using the VICTOR Nivo plate reader.
Flyer
Reagent solutions for virology research
Discovery a range of immunoassays and other products Revvity offers to help you save time, increase your productivity in virology research.
Application Note
Advancing autophagy detection: HTRF LC3B-II assay for specific and reliable LC3B-II detection
This study validates the HTRF LC3B-II immunoassay as a reliable, precise, and faster alternative to the traditional LC3 Western Blot for quantifying autophagy in various cellular models.
Application Note
Modulation of Bcl-2 Expression in MCF7 Cells Using LANCE TR-FRET Technology
This study demonstrates the effectiveness of LANCE Ultra TR-FRET assay technology in identifying and characterizing Bcl-2 protein expression in MCF7 cells, with expression levels modulated by agents that induce cell death and affect proliferation. The assay’s versatility is further highlighted by its application to suspension cell lines and frozen cellular lysates.
Infographic
Ditch the wash steps and accelerate discovery
ELISA immunoassays are great, but what if you could improve sensitivity and increase dynamic range all while eliminating wash steps and saving time?
Application Note
Tracking inflammasome activity via measuring IL-1β levels with AlphaLISA and HTRF
This application note demonstrates the utility of AlphaLISA™ and HTRF™ for the detection of IL-1β in cell supernatant and serum samples which can be used as a biomarker for inflammasome activity
Application Note
Excellent sensitivity from the EnVision Nexus multimode plate reader for AlphaLISA detection
This application note demonstrates the AlphaLISA detection capabilities of the EnVision Nexus and compares it to the EnVision 2105.
Whitepaper
Accelerating immuno-oncology therapeutic development: choosing the best preclinical model
Selecting the appropriate preclinical model for immuno-oncology therapeutic development.
Application Note
Guidelines for optimization of a cell-labelling method for DELFIA-TRF cytotoxicity assays.
Discover expert guidelines for optimizing cell labeling in DELFIA TRF cytotoxicity assays. Learn how to enhance assay performance, manage spontaneous release, and achieve accurate results with this comprehensive application note.
Literature - Publication Review
hESC-derived cardiomyocyte screening platform identifies novel inhibitors of SARS-Cov-2 viral entry
Understand the pathology of SARS-CoV-2 in cardiomyocytes with a screening platform using human embryonic stem cell dervied cardiomyocytes (hESC-CMs)
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