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Whitepaper
Relevance of multiparametric screening to drug discovery efforts
This white paper explores the importance of multiparametric screening to drug discovery efforts
Application Note
Machine-learning prediction of drug mechanism of action from high-content cell painting images
This application note demonstrates how machine-learning and high-content imaging can be applied to predict drug mechanism of actions.
Brochure
Vanadis NIPT system
Outlines differentiating features of the Vanadis NIPT system, inclusive of minimal hands-on time, walkaway automation, high precision and no PCR or sequencing. Empowering any laboratory to conduct NIPT in-house.
Brochure
Vanadis cfDNA platform
Highlights the defining features behind the Vanadis cfDNA platform, including its ease of use, full automation, high precision and no PCR or sequencing required. Now any lab can conduct cfDNA analysis in-house.
Infographic
The impact of no-call rate in NIPT
A reference that highlights the clinical importance of no-call rate in NIPT (non-invasive prenatal testing).
Whitepaper
Conditional knockout generation using targeted exon excision and synthetic introns
This white paper explores approaches for conditional knockout generation using targeted exon excision and synthetic introns.
Literature - Publication Review
SVEP1 as a regulator of GPCR-mediated vasoconstriction
This literature review describes how scientists uncovered multifunctional roles of SVEP1, a known contributor to cardiovascular disease.
Whitepaper
Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.
Application Note
Effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in high-content analysis screening experiments
Find out about the effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in HCA screening experiments.
Application Note
Pooled phenotypic CRISPR screening enables the identification of synergistic drug combinations for cancer therapy
This application note demonstrates how a pooled phenotypic CRISPR screening can be used to identify synergistic drug combinations for cancer therapy
Literature - Publication Review
Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.
Whitepaper
Overcoming hurdles in high-throughput profiling of cancer cell responses
Presenting case studies on how functional genomic screening is used to find therapeutic targets, identify patient populations, uncover MoA, investigate drug combinations, and reveal drug resistance and sensitivity
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