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Article
Selective targeting of mHTT presents novel therapeutic approach to huntington's disease
Researchers have engineered zinc finger protein transcription factors (ZFP-TFs) to target the pathogenic CAG repeat and selectively lower mHTT as a therapeutic strategy.
Whitepaper
Meet the scientist: uncovering the pathways dictating evolution of lung cancer heterogeneity
Understanding why tumors evolve from a single cell to a heterogenous tissue could direct the development of new therapies.
Infographic
Precision medicine research, for sharper decisions
Precision medicine can lead to sharper decision making through functional and molecular stratification.
Literature - Publication Review
Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.
Article
Tackling Huntington's disease from all angles
Huntington's Disease research to better characterize early stages of the disease and discover new treatment therapies, while lending support to HD patients and families.
Whitepaper
Expert interview: cancer resistance to immunotherapy
Understand the Mechanisms behind Cancer Resistance to Immunotherapy
Whitepaper
Spotlight research interview: narcolepsy, a neurological autoimmune disorder
Researchers were first to demonstrate direct evidence of autoreactive immune cells in narcolepsy patients, providing evidence of autoimmune basis
Literature - Publication Review
Prolonging ß cell proliferation with a 3D culture system
Disque Platform technology for evaluating drug candidates to treat ß cell loss in patients with diabetes.
Whitepaper
COVID-19 therapeutics: demand, challenges, and the future
Whitepaper provides insights into why developing effective COVID-19 treatments plays a significant role in pandemic control and explores therapeutic approaches pursued.
Article
Research spotlight interview: the role of biomarkers in drug discovery for neurodegenerative disease
Researcher takes a multidisciplinary approach in defining early biomarkers of dementia.
Whitepaper
Huntington’s disease: progress and future perspectives
Insight into recent scientific breakthroughs and therapeutic approaches currently being pursued by the HD research community.
Whitepaper
Leveraging the microbiome to strengthen immune therapeutic response
Understanding the role bacteria play, whether it be oncogenesis, tumor promotion, or treatment effectiveness, may provide an opportunity for intervention at the microbiome level in favor of cancer regression.
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