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Article
Selective targeting of mHTT presents novel therapeutic approach to huntington's disease
Researchers have engineered zinc finger protein transcription factors (ZFP-TFs) to target the pathogenic CAG repeat and selectively lower mHTT as a therapeutic strategy.
Whitepaper
Meet the scientist: uncovering the pathways dictating evolution of lung cancer heterogeneity
Understanding why tumors evolve from a single cell to a heterogenous tissue could direct the development of new therapies.
Infographic
Precision medicine research, for sharper decisions
Precision medicine can lead to sharper decision making through functional and molecular stratification.
Literature - Publication Review
Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.
Infographic
Solutions for virology research
Virology research solutions to enable virus monitoring, neutralization testing, as well as viral pathogenesis studies.
Whitepaper
Leveraging the microbiome to strengthen immune therapeutic response
Understanding the role bacteria play, whether it be oncogenesis, tumor promotion, or treatment effectiveness, may provide an opportunity for intervention at the microbiome level in favor of cancer regression.
Whitepaper
Spotlight research interview: narcolepsy, a neurological autoimmune disorder
Researchers were first to demonstrate direct evidence of autoreactive immune cells in narcolepsy patients, providing evidence of autoimmune basis
Literature - Publication Review
Prolonging ß cell proliferation with a 3D culture system
Disque Platform technology for evaluating drug candidates to treat ß cell loss in patients with diabetes.
Article
Research spotlight interview: the role of biomarkers in drug discovery for neurodegenerative disease
Researcher takes a multidisciplinary approach in defining early biomarkers of dementia.
Literature - Publication Review
Establishing a baseline and drug-induced SMN expression profile in SMA disease-relevant human tissues in expedited autopsies
Research in establishing SMN expression level baselines in disease-relevant human tissues across.
Whitepaper
Huntington’s disease: progress and future perspectives
Insight into recent scientific breakthroughs and therapeutic approaches currently being pursued by the HD research community.
Whitepaper
Expert interview: cancer resistance to immunotherapy
Understand the Mechanisms behind Cancer Resistance to Immunotherapy
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