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Literature - Publication Review
Research and characterization of bispecific antibodies for cancer immunotherapies
In this literature review, we describe several functional approaches to characterize novel BsAbs targeting immune checkpoints and the tumor necrosis factor (TNF) superfamily, with easy-to-use immunoassays.
Application Note
DELFIA VICTOR Immunoassays- How to Optimize Rapid and Simple Immunoassays
In this application note, parameters affecting the performance characteristics of rapid and simple immunoassays have been optimized. These parameters were temperature, concentration of immunocomponents, dynamics (including diffusion), and the quality of immunocomponents.
Application Note
Developing novel tetraubiquitin substrates and AlphaLISA technology to provide next generation deubiquitinase assays
This application note presents novel biochemical DUB assays that use TUBEs to bind to tetraubiquitin substrates of at least three natural linkages. These assays, combined with Revvity’s AlphaLISA™ technology, allow for the measurement of protein interactions and large protein complexes in a no-wash, homogeneous assay.
Literature - Publication Review
Literature review on protein-protein interaction assays for virology research
This literature review reviews recent publications and show the homogeneous assay set-ups used in a variety of different studies. We present the outcomes of each study and how the information gathered could lead to antiviral therapies.
Literature - Publication Review
Novel drugs for cancer therapy development with PROTAC
A review of current homogeneous assay applications for PROTACs
Literature - Publication Review
Novel drugs for cancer therapy development with PROTAC
A review of current homogeneous assay applications for PROTACs
Application Note
Detection of human matrix metalloproteinase 9 in complex sample matrices, a comparison of AlphaLISA and colorimetric ELISA immunoassays
This note compares two immunoassay technologies: ELISA (enzyme-linked immunosorbent assay) and AlphaLISA™ (amplified luminescent proximity-based homogeneous assay).
Literature - Publication Review
Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.
Application Note
HMGB1, IL-1β and IL-18 assays used together to discriminate pyroptosis and necroptosis
This application note shows that the release of HMGB1 induced in the context of pyroptosis and necroptosis can be easily monitored with the HTRF® HMGB1 kit.
Application Note
Download your application note on fibrosis characterization
This note describes deep investigations of the molecular mechanisms involved in tissue fibrosis, and occurring in the major effector cell types.
Application Note
Download your application note on nuclear receptor ligand identification with HTRF
This application note illustrates the use of HTRF PPI reagents to easily build robust and convenient biochemical NR/ CoA recruitment assays.
Literature - Publication Review
HTRF and AlphaLISA solutions in inflammatory bowel diseases research
This note groups four scientific publications which spotlight the use of HTRF and Alpha solutions applied to IBD research.
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