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Application Note
2D OncoSignature™ Long-Term Assay: Extending the reach of cell panel screens
This application note describes the development of the 2D OncoSignature™ Long-Term Assay (LTA) drug discovery service.
Application Note
Development of a near infrared fluorescent labeled agent for assessing bombesin receptor expression in cancer
This application note highlights using IVISense Bombesin Receptor fluorescent probe to assess bombesin receptor expression in cancer
Application Note
Advancing autophagy detection: HTRF LC3B-II assay for specific and reliable LC3B-II detection
This study validates the HTRF LC3B-II immunoassay as a reliable, precise, and faster alternative to the traditional LC3 Western Blot for quantifying autophagy in various cellular models.
Application Note
Modulation of Bcl-2 Expression in MCF7 Cells Using LANCE TR-FRET Technology
This study demonstrates the effectiveness of LANCE Ultra TR-FRET assay technology in identifying and characterizing Bcl-2 protein expression in MCF7 cells, with expression levels modulated by agents that induce cell death and affect proliferation. The assay’s versatility is further highlighted by its application to suspension cell lines and frozen cellular lysates.
Application Note
Kinetic analysis of calcium flux activity in human iPSC-derived neurons using the Opera Phenix Plus system
Application note for fast kinetic imaging using HCS to visualize and evaluate spontaneous calcium flux activity in single human iPSC-derived neurons
Application Note
Measuring FRET using the Opera™ Phenix™ high-content screening system
Here, we present a FRET-based high-content screening assay to study the interaction of the anti-apoptotic protein Bcl-XL with the pro-apoptotic protein Bad.
Application Note
Imaging bile canaliculi in 3D liver microtissues
Here, we describe a 3D HCS assay to study hepatobiliary transporter function in InSphero human liver microtissues using the Opera Phenix™ HCS system.
Application Note
Background correction and dependency on quench.
Guide to preparing suitable background samples for accurate scintillation measurements in environmental and natural radioactivity studies, focusing on composition matching and key considerations.
Application Note
How can I prepare a protocol for a GCT optimization run?
How to optimize Quantulus GCT 6220's Guard Compensation Technology for background reduction, focusing on proper background sample preparation and protocol creation.
Application Note
Requirements for a “good“ measurement with a liquid scintillation counter.
Guide to achieving accurate liquid scintillation measurements, covering sample preparation, instrument maintenance, protocol settings, and data output for optimal results and minimal uncertainty.
Application Note
Imaging oncolytic virus infection in cancer cells
IVIS ® optical imaging to assess and quantify oncolytic viral infection in living tumors and the subsequent virus-host interactions in real-time.
Application Note
Preclinical imaging for stem cell research and regenerative medicine
This application note highlights the use of the IVIS optical imaging platform for stem cell and regenerative medicine research
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