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Application Note
Effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in high-content analysis screening experiments
Find out about the effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in HCA screening experiments.
Application Note
Pooled phenotypic CRISPR screening enables the identification of synergistic drug combinations for cancer therapy
This application note demonstrates how a pooled phenotypic CRISPR screening can be used to identify synergistic drug combinations for cancer therapy
Application Note
CRISPRsc: Pooled CRISPR screening with single-cell transcriptome resolution
This application note describes a pooled CRISPR screen with single-cell transcriptome resolution to link gene expression signature with drug response.
Application Note
CRISPR-Cas9 screening for target identification
Explore the power of whole-genome CRISPR-Cas9 screening in this application note.
Application Note
CRISPRa: Transcriptional upregulation screening with genome-wide CRISPR activation
This application note demonstrates transcriptional upregulation screening with genome-wide CRISPR activation.
Application Note
The dual screen: Parallel genome-wide CRISPRi and CRISPRa screening
Discover the advantages of a dual screen using CRISPRi and CRISPRa screening in parallel in this application note.
Application Note
CRISPRi: Transcriptional repression screening with genome-wide CRISPR interference
This application note demonstrates transcriptional regression screening with a novel whole-genome CRISPRi platform.
Application Note
Target essentiality assay
This application note demonstrates Revvity’s target essentiality assay which indicates whether or not a specific gene is essential for survival and/or proliferation in a given cell line.
Application Note
Profiling compound effect on immune cells by combining ImmuSignature assays and LEGENDplex bead-based multiplex protein quantification
Explore Revvity's preclinical services for cell engineering and screening in our ebook.
Application Note
Flow cytometry sample preparation is faster and more accurate with FlexDrop Plus
Flow cytometry sample preparation is faster and more accurate with FlexDrop Plus. In this application note, the researchers compared different liquid handling systems for dispensing these colored antibodies. They focused on how fast the system worked, how much liquid was wasted, and how reliable it was.
Application Note
Cell labeling and tracking in vivo using IVISense NIR fluorescent dyes
Track mammalian cells including stem cells, T-cells, macrophages and more in vivo with IVISense™ (VivoTrack) fluorescent labeling dye
Application Note
Evaluation of drug selectivity and efficacy using PROTACs in a 3D co-culture spheroid model
The aim of this study was to evaluate the efficacy and selectivity of SJF1528, a pan-EGFR PROTAC, and MS39, a mutant-specific EGFR L858R PROTAC, while exploring the use of both high-content imaging and no-wash HTRF immunoassays in encapsulated 3D spheroid models.
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