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Distinguishing cell types by phenotypic profiling of the nucleus
As nearly all screening approaches require a nuclear counterstain, phenotypic profiling of the nuclei can offer new insights on assays at no extra cost.
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Fast Kinetic Calcium Flux Imaging Using the Opera Phenix Plus High-Content Screening System
Application Note - Fast Kinetic Calcium Flux Imaging Using the Opera Phenix Plus High-Content Screening System.
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Multi-parametric high-throughput analysis of hepatotoxicity using a 3D primary liver cell culture model
The creation of an advanced 3D primary human hepatocyte (PHH) model using the RASTRUM platform that seamlessly integrates with Revvity’s HTS technologies.
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Phenotypic analysis of hypertrophy in human iPSC-derived cardiomyocytes
Application note describing phenotypic analysis of hypertrophy in human iPSC-derived cardiomyocytes using the Opera Phenix high-content screening system
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Measuring FRET using the Opera™ Phenix™ high-content screening system
Here, we present a FRET-based high-content screening assay to study the interaction of the anti-apoptotic protein Bcl-XL with the pro-apoptotic protein Bad.
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Imaging bile canaliculi in 3D liver microtissues
Here, we describe a 3D HCS assay to study hepatobiliary transporter function in InSphero human liver microtissues using the Opera Phenix™ HCS system.
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Analyzing ERK signal transduction in live cells using a FRET-based biosensor
Application note describing analysis of ERK signal transduction in live cells using a FRET-based biosensor with the Operetta CLS high-content analysis system.
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A novel method for the determination of cyclosporine in rabbit ocular tissues by LC-MS/MS
Multi-sample bead mill homogenization for extraction of cyclosporine from ocular tissues.
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