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Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
Article
Selective targeting of mHTT presents novel therapeutic approach to huntington's disease
Researchers have engineered zinc finger protein transcription factors (ZFP-TFs) to target the pathogenic CAG repeat and selectively lower mHTT as a therapeutic strategy.
Case Study
Assessment of MYC-driven progression of small cell lung cancer
Researchers at Huntsman Cancer Center use GEMM and the Quantum microCT system for evaluating small cell lung cancer.
Article
cst-research-spotlight-qa-alves-opioids-bone-homogenization
Method development for toxicological analysis of synthetic opioids from bone.
Case Study
Optical and microCT imaging enables noninvasive monitoring of EBV-induced neuroinvasion
Researchers use optical and microCT imaging to noninvasively monitor EBV-induced neuroinvasion in a mouse model.
Case Study
A novel mouse model using optical imaging to detect on-target, off-tumor CAR-T cell toxicity
A Novel Mouse Model Using IVIS® Optical Imaging to Detect On-Target, Off-Tumor CAR-T Cell Toxicity.
Case Study
NIH NCATS case study: using accelerated screening research for SARS-CoV-2 drug repurposing candidates
Find out how the NCATS team was able to quickly screen 3,384 molecular entities and narrow them down to a field of 25 quality "hits" capable of disrupting SARS-Cov-2 S1 protein:ACE2 receptor binding in this case study.
Case Study
Assessing murine glioblastoma growth: a comparative study of ultrasound and MRI imaging modalities
Comparison of MRI with the Vega™ ultrasound system and VesselVue™ agent to track glioblastoma growth in a murine model.
Case Study
Improving the throughput of a neuroprotection assay using the opera phenix high content screening system
Download the case study to learn how primary neuron morphology is analyzed in a straightforward approach using Harmony® software and careful assay optimization can increase throughput, and minimize the data burden, without compromising assay performance.
Case Study
Re-tooling anti-microbial research for the 21st century
Case study describing the analysis of bacterial phenotypes to investigate adaptive mechanisms of antimicrobial resistance and screening for novel alternatives.
Case Study
A scalable method to monitor protein levels and localizations in cells
Pooled protein tagging, cellular imaging, and in-situ sequencing to identify cellular response to drug treatment.
Article
Research spotlight interview: Combining expertise in 3D airway cell models with SARS-CoV-2 research
A study on the first interaction of SARS-CoV-2 with host respiratory tissues.
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