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Biopolymers Codelivering Engineered T Cells and STING Agonists can Eliminate Heterogenous Tumors
Using the IVIS® Spectrum non-invasive preclinical optical system to quantify tumor-specific T cells responses in NFAT-luciferase transgenic mice.

Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.

Streamlining single-cell sequencing workflows using Cellometer and Cellaca high-throughput cell counters
Literature review for Cellometer and Cellaca titled Streamlining single-cell sequencing workflows using Cellometer and Cellaca high-throughput cell counters

Improving precision stratification using patient-derived model systems
Precision stratification using patient-derived model systems.

Evaluating a novel nanoparticle platform for controlled liraglutide release in a Type II diabetes mouse model
Optical imaging using the IVIS® Platform to evaluate a novel nanoparticle system for controlled liraglutide release in a diabetic mouse model.

Improving engineered T cell efficacy for treating solid tumors through epigenetic modulation
Researchers used the Opera Phenix® HCS and IVIS® preclicinal imaging system to evaluate engineered T-cells through epigenetic modulation showing the potential of improving the cytotoxic effects on solid tumors.

In vivo imaging of influenza virus infection in immunized mice
Using the IVIS® in vivo imaging platform to quantifiy H1N1pmd09-Nluc influenza viral load in mice and demonstrated that human mAb administration has a protective or therapeutic effect in mice challenged with influenza virus.

Applications of In Vivo bioluminescence imaging for SARS-CoV-2
Scientists utilize non-invasive in vivo bioluminescence imaging to study SARS-CoV-2 progression, immune response and drug therapies.

Exploring mechanisms behind alphavirus-induced post-encephalitic parkinsonism
neuroinvasive viruses eliciting neurodegenerative symptoms of post-encephalitic parkinsonism by using bioluminescent or fluorescent recombinant WEEV in an in vivo mouse model

A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency
Researchers design an adeno-associated virus (AAV) 6 capsid that demonstrates efficiency in lung epithelial cell transduction in a mouse model validated using optical imaging.

Deciphering the properties of neuronal nicotinic acetylcholine receptors using radiolabeled α-Bungarotoxin
Deciphering the Properties of Nicotinic Acetylcholine Receptors Using 125I-α-Bungarotoxin

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development
Dr. Kawaoka Yoshihiro, a world-renowned virologist uses the Quantum microCT system to study SARS-CoV-2 in Syrian hamster models.


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