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Deciphering the role of neutrophils in virus-induced respiratory disease
Preclinical imaging of neutrophilic response in viral infection with IVISense™ Neutrophil Elastase fluorescent probes.

Meet the scientist: uncovering the pathways dictating evolution of lung cancer heterogeneity
Understanding why tumors evolve from a single cell to a heterogenous tissue could direct the development of new therapies.

Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.

Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.

The importance of combination therapy for modern cancer treatments
This white paper discusses the importance of combination therapy for modern cancer treatments.

Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models

Bioluminescence Resonance Energy Transfer (BRET) to monitor protein-protein interactions
The ability to image PPIs in vivo has important implications for a wide variety of biological research endeavors, including drug discovery and molecular medicine.

Non-invasive optical imaging for viral research and novel therapeutic and vaccine development
Non-invasive optical image using IVIS ® systems for pre-clinical viral research.

Accelerating immuno-oncology therapeutic development: choosing the best preclinical model
Selecting the appropriate preclinical model for immuno-oncology therapeutic development.

Eyes on synaptotagmin 7 (SYT7) in synaptic function and neuroplastic health for cognitive decline
Researcher, Dr. Jason Vevea, describes the role of synaptotogmin 7 in the synaptic vesicle cycle and the experimental steps taken to discover that SYT7 supports asynchronous release, short-term synaptic plasticity, and synaptic vesicle replenishment.

Research spotlight: new therapeutic targets focusing on aberrant lipid metabolism in Alzheimer’s disease
This whitepaper explores new therapeutic targets focusing on Aberrant Lipid Metabolism in Alzheimer's Disease

Antibody-based therapeutic modalities in oncology
Explore monoclonal antibody-based cancer therapeutics in this white paper, covering mechanism of action, development, and challenges.


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