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Applying functional genomics strategies to high-content phenotypic screening
Explore cutting-edge functional genomics and high-content phenotypic screening in drug discovery. Download our whitepaper to learn about innovative techniques, best practices, and strategies for leveraging high-content imaging methods like cell painting to advance your research. Unlock the potential of genomic profiling and morphological analysis for therapeutic interventions

ImmuSignature™ MLR: Rapid high-throughput assessment of therapeutic immunogenicity
This white paper describes how a rapid immunogenicity assessment screening can provide invaluable support for IND applications.

Assessing the epigenetics of T cell exhaustion using CRISPR screens
Explore the epigenetics of T cell exhaustion and practical techniques to assess immune cell epigenetic regulators using CRISPR screens.

Base editing and stem-cell based therapies
This white paper explores how base editing is advancing iPSCs in the fields of basic science, regenerative medicine and immunotherapy.

Addressing the challenges in solid tumor therapy with base editing
Read this white paper to learn about how base editing is helping to address key challenges in immunotherapies for solid tumors.

Overcoming hurdles in high-throughput profiling of cancer cell responses
Presenting case studies on how functional genomic screening is used to find therapeutic targets, identify patient populations, uncover MoA, investigate drug combinations, and reveal drug resistance and sensitivity

CRISPR-Cas9 screening: a powerful approach to advance drug discovery
Find out about the potential of CRISPR-Cas9 screening for drug discovery in this white paper.

Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.

CRISPR-derived base editing technology: The what, the how, and the why
This white paper provides a comprehensive guide to base editing, including what it is, how it works and applications.

Preclinical screening platforms for antibody-drug conjugate therapeutics
Learn more about ADCs and the role that screening can play to help advance the discovery process for ADC therapeutic candidates in this white paper.

The importance of combination therapy for modern cancer treatments
This white paper discusses the importance of combination therapy for modern cancer treatments.

How CRISPR-based functional genomics is transforming drug discovery
Exploring how functional genomics is used in preclinical drug discovery with target identification, drug response mechanisms, and in vivo tumor biology.


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