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Application Note

BioQule DNA-Seq library prep: Samples to ready-to-use NGS libraries

Learn about the the BioQule DNA Library Prep Kit, which utilizes enzymatic fragmentation, and the BioQule NGS System for Whole Genome Sequencing (WGS).

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Guide

AlphaLISA immunoassay conversion quick start guide

This quick guide presents a fast proof-of concept experiment to easily convert a immunoassay to a no-wasy AlphaLISA assay.

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Technical Note

AlphaLISA tri-methyl-Histone H3 lysine 27 (H3K27me3) cellular detection kit

The AlphaLISA™ immunodetection assay tracks variations in cellular extract levels of tri-methylated histone H3 lysine 27 (H3K27me3).

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Technical Note

AlphaLISA JMJD3 Histone H3-Lysine 27 demethylase assay

This AlphaLISA immunodetection assay measures the demethylation of a biotinylated Histone H3 (21-44) peptide tri-methylated at lysine 27.

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Technical Note

Exposing and detecting membrane and intracellular proteins: AlphaLISA simplifies the detection of HO-1

This technical document reveals the application of AlphaLISA technology in measuring HO-1 concentrations within HeLa cell extracts.

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Technical Note

Development of an AlphaLISA MEK1 kinase assay using full-length ERK2 substrate

This technical note illustrates one example of how these toolbox beads may be used to efficiently develop an assay for assessing MEK1 phosphorylation of a native ERK2 substrate.

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Technical Note

AlphaLISA in urine: Detecting kidney injury marker KIM-1

This document highlights the capability of AlphaLISA technology to identify the kidney injury biomarker KIM-1 in urine samples, achieving detection levels as low as 14 pg/mL.

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Technical Note

AlphaLISA PRMT6 Histone H3-Arginine N-methyltransferase assay

This AlphaLISA immunoassay detects the mono-methylation of a biotinylated Histone H3 (1-21) peptide at lysine 4.

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Technical Note

AlphaLISA HDAC1 Histone H3-Lysine 27 deacetylase assay

In this technical note discover how The AlphaLISA assay detects detect the removal of acetyl groups from a biotin-tagged peptide derived from Histone H3.

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Technical Note

AlphaLISA LSD1 Histone H3-Lysine 4 demethylase assay

This AlphaLISA immunodetection assay measures the demethylation of a biotinylated Histone H3 (1-21) peptide mono‑methylated at lysine 4.

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Technical Note

Detection of immune checkpoint markers in peripheral blood mononuclear cell lysates with AlphaLISA

In this technical note, discover how AlphaLISA can be used to detect and quantify additional immune checkpoint molecules within the PBMC population with and without activation using Dynabeads®.

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Technical Note