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Literature - Publication Review
HTRF and AlphaLISA assays bring clarity to extracellular matrix related fibrosis development
This note gathers publications that exemplify various applications of HTRF™ and AlphaLISA™ assays to advance fibrosis related research and shows how other researchers have harnessed these technologies to move their studies forward.
Application Note
Avoiding biotin interference in AlphaLISA assays
This application note demonstrates the value of using AlphaLISA biotin-free kits to reduce the effects of biotin interference in sample and standard preparations.
Application Note
Rapid, no-wash measurement of immune checkpoint molecules and cytokines in co-cultures of immune cells and cancer cell lines
Download this application note to learn how to rapidly measure multiple biomarkers in cell culture supernatant and lysates
Application Note
A comparative study of two immunoassay platforms to determine lentivirus titer for CAR-T development
This application note demonstrates a comparative quantification of the p24 titer in a lentiviral GFP control sample using Alliance HIV-1 p24 Antigen ELISA and p24 AlphaLISA immunoassay platforms.
Application Note
Protocol optimization for detection and quantification of membrane-bound proteins using AlphaLISA technology
AlphaLISA kits have the capability to assess hundreds of targets, including cytokines, proteins circulating in the blood, and cellular proteins.
Application Note
Characterizing chemokine receptor inhibitors with AlphaLISA SureFire Ultra, Alpha SureFire Ultra Multiplex and LANCE Ultra cAMP assays
This application note demonstrates how the SureFire Ultra and LANCE Ultra cAMP assays can be used for measuring inhibitors to CCR7 and CXCR2 cell surface receptors using a cellular model system where these receptors are overexpressed in CHO cells.
Whitepaper
Shifting the treatment paradigm: the promise of gene therapy for neurodegenerative diseases
Traditional treatments for neurodegenerative diseases focus on managing symptoms, but recent advancements in gene therapy offer hope for more effective and sustainable solutions. Read now!
Whitepaper
Targeted protein degradation: A novel therapeutic strategy for neurodegenerative diseases
In this white paper, get details about TPD that offers a novel strategy for neurodegenerative diseases by degrading disease-linked proteins, showing promise in preclinical studies.
Whitepaper
Exploring the strengths, challenges, and therapeutic applications of multispecific antibodies
Discover the latest advancements in multispecific antibodies and their transformative potential in treating complex diseases. Download our comprehensive white paper now!
Application Note
Biochemical binding ADCC assays utilizing AlphaLISA toolbox reagents for the characterization of hIgGs and FcγR1A
In this application note we demonstrate the ease with which AlphaLISA toolbox reagents can be used to develop any FcγR binding assay across the various stages of biologics research and development, including therapeutic screening and GMP Lot Release.
Application Note
A fast and simple chemiluminescent assay for monitoring of DNA-protein interactions
In this application note, we use HepG2 nuclear extracts to demonstrate the binding of Sp1 and HNF1 transcription factors to tagged oligonucleotides containing required cognate response elements. Read this note to see the results and access detailed data compared to EMSA.
Technical Note
AlphaLISA Acetyl‑Histone H3 lysine 27 (H3K27ac) cellular detection kit
This AlphaLISA immunodetection assay detects alterations in acetylated histone H3 lysine 27 (H3K27ac) levels within cellular extracts.
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