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Increasing the targeting scope and precision of next-generation gene editing technology
In this application note, we demonstrate the Pin-point™ base editing system as a novel nucleaseagnostic modular platform for increasing the targeting scope and precision of next-generation gene editing technology.

Cellometer X2 fluorescent cell viability counter: A rapid method for Candida albicans culture sample stability determination.
Application Note using the Cellometer X2 fluorescent cell viability counter to determine Candida albicans culture sample stability.

Empowering T cell therapies: the strategic use of LentiBOOST in CAR T and TCR modalities
This literature review demonstrates how the LentiBOOST™ transduction enhancer can be applied to CAR T and TCR modalities.

Image-Based CAR-T Cell Assays for Apoptosis and CAR Expression Monitoring
This poster introduces a new image-based method to monitor CAR expression and apoptosis in CAR-T cells, offering insights into cell viability post-gene delivery.

Optimization of Modular Pin-point™ Base Editing with Type V CRISPR-Cas
This poster details advancements in the Pin-point™ base editing platform, focusing on modularity and efficiency improvements with Type V CRISPR-Cas effector applications in gene therapy.

Enhanced iPSC Editing with Minimal p53 Activation via Pin-point™
Focused on improving iPSC editing, this poster discusses reduced p53 pathway activation with Pin-point™ cytidine base editing, enhancing cell viability and therapeutic outcomes.

Custom gRNA Design and Efficiency Prediction in Pin-point™ Editing
This poster discusses the development of custom guide RNA (gRNA) design tools and efficiency prediction models, enhancing Pin-point™ base editing accuracy in gene therapy applications.

Advancements in Pin-point™ Base Editing for Targeted Gene Therapy
This poster showcases the latest improvements in the Pin-point™ base editing platform, emphasizing applications in targeted gene therapy for enhanced therapeutic outcomes.

Multi-Omic Analysis of Immune Cells Using Pin-point™ Base Editing
Presenting multi-omic analysis techniques for immune cells edited with Pin-point™, this poster uncovers insights into cell engineering outcomes in CAR-T therapies.

Development of a High-Efficiency RNA-Guided Base Editing System
Presenting a high-efficiency RNA-guided base editing platform, this poster explores increased precision in gene editing applications, suitable for cell therapy advancements.

Modular Pin-point™ Base Editing for Multi-Target Efficiency
Detailing the modular capabilities of the Pin-point™ base editing platform, this poster examines its role in multi-gene targeting for streamlined cell therapy applications.

SMARTvector™ Multiplex shRNA for Enhanced Cell Therapy Safety
Explore the SMARTvector™ multiplex shRNA platform for safe, multi-target gene knockdown in cell therapy applications, offering new levels of therapeutic control and safety.


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