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Application Note
Developing novel tetraubiquitin substrates and AlphaLISA technology to provide next generation deubiquitinase assays
This application note presents novel biochemical DUB assays that use TUBEs to bind to tetraubiquitin substrates of at least three natural linkages. These assays, combined with Revvity’s AlphaLISA™ technology, allow for the measurement of protein interactions and large protein complexes in a no-wash, homogeneous assay.
Application Note
Detection of human matrix metalloproteinase 9 in complex sample matrices, a comparison of AlphaLISA and colorimetric ELISA immunoassays
This note compares two immunoassay technologies: ELISA (enzyme-linked immunosorbent assay) and AlphaLISA™ (amplified luminescent proximity-based homogeneous assay).
Literature - Publication Review
Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.
Whitepaper
Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models
Infographic
Why 3D: stripping complexity out of multi-dimensional cell models
Bridging the gap between 2D Cell cultures and in vivo conditions.
Scientific Poster
Brightfield and Fluorescent Image Analysis for Screening Applications using the Celigo Adherent Cell Cytometer
Brightfield and Fluorescent Image Analysis for Screening Applications using the Celigo Adherent Cell Cytometer
Scientific Poster
Cell-mediated cytotoxicity assay by high-throughput direct cell counting in microplates using fluorescence-based image cytometry
Cell-Mediated Cytotoxicity Assay by High-Throughput Direct Cell Counting in Microplates using Fluorescence-Based Image Cytometry
Scientific Poster
A high-throughput image cytometry-based screening method for the detection of IL2-induced peripheral blood mononuclear cell-mediated cytotoxicity
A high-throughput image cytometry-based screening method for the detection of IL2-induced peripheral blood mononuclear cell-mediated cytotoxicity
Scientific Poster
Real-time Caspase 3/7 measurement of suspension and adherent cells using the Celigo image cytometer
Real-time Caspase 3/7 measurement of suspension and adherent cells using the Celigo image cytometer
Scientific Poster
Validating and optimizing single cell sorting of FACS using Celigo image cytometry
Validating and optimizing single cell sorting of FACS using Celigo image cytometry
Application Note
Evaluating HTRF and AlphaLISA SureFire Ultra detection methods in GrowDex-supported 3D MCF7 cell cultures
Application note describing the evaluation of HTRF and AlphaLISA SureFire Ultra detection methods in GrowDex-supported 3D MCF7 cell cultures.
Article
Top tips for effective gene silencing in 3D cultures
Discover how to achieve efficient gene knockdown in 3D cell cultures.
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