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Application Note
CRISPRa: Transcriptional upregulation screening with genome-wide CRISPR activation
This application note demonstrates transcriptional upregulation screening with genome-wide CRISPR activation.
Application Note
The dual screen: Parallel genome-wide CRISPRi and CRISPRa screening
Discover the advantages of a dual screen using CRISPRi and CRISPRa screening in parallel in this application note.
Application Note
CRISPRi: Transcriptional repression screening with genome-wide CRISPR interference
This application note demonstrates transcriptional regression screening with a novel whole-genome CRISPRi platform.
Flyer
Preclinical services reading list
Selected publications that utilizes Revvity’s Preclinical Services to enhance scientific research and progress drug discovery.
Application Note
Target essentiality assay
This application note demonstrates Revvity’s target essentiality assay which indicates whether or not a specific gene is essential for survival and/or proliferation in a given cell line.
Whitepaper
How CRISPR-based functional genomics is transforming drug discovery
Exploring how functional genomics is used in preclinical drug discovery with target identification, drug response mechanisms, and in vivo tumor biology.
Webinar
CHOSOURCE™ GS KO cell line: optimization, improvement strategy, and case study
On-demand webinar showing how to enhance bioprocess in CHO cell lines through molecular design, screening, and process optimization strategies, utilizing the CHOSOURCE expression platform.
Whitepaper
Advancing biotherapeutic development with transposon-based technologies
Discover how to generate highly producing pools early on in your development workflow with transposon technology and accelerate time to clinic
Scientific Poster
CHOSOURCE ADCC+ cell line for enhanced therapeutic potency
Discover how the CHOSOURCE ADCC+ cell line increases Antibody Dependent Cellular Cytotoxicity (ADCC) for use in the production of biotherapeutics for oncology, anti-infectives and auto-immune diseases.
Scientific Poster
Application of gene editing technologies to improve biotherapeutic manufacturing
Showcasing a multiplex gene editing approach with well-defined workflows and established tools to isolate, identify, and characterize edited knock-out or knock-in clones in different cell types.
Scientific Poster
Integration of next-generation transposon vectors with state-of-the-art host cell lines
Presenting the performance data of CHOSOURCE TnT expressing a standard immunoglobulin G (IgG) molecule with CHOSOURCE CHO-K1 GS KO and ADCC+ cell lines
Webinar
Webinar. Are you stable or transient? Optimize your biotherapeutic cell line workflows
Hear how Jounce integrated Revvity’s CHOSOURCE GS cell line into their drug development workflow to improve efficiencies
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