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One-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform
Discover one-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform.

Organoid Week Webinar Series - Part 4: High throughput approaches to 3D imaging
Join us on-demand for Part 4 of our Organoid Week Webinar Series. Discover insightful sessions from organoid industry experts.

Base Editing of Human Hematopoietic Stem and Progenitor Cells with the Base Editing of Human Hematopoietic Stem and Progenitor Cells with the Pin-point™ platform
Learn why the Pin-point™ base editing platform is a valuable tool for the generation of advanced cell therapies using sensitive cell types.

LentiBOOST transduction enhancer
This flyer provides an overview of the LentiBOOST transduction enhancer technology.

Advancing Gene Editing Efficiency and Precision with the Pin-point™ Base Editing Platform
This webinar discusses how the Pin-point™ base editing platform can achieve more efficient and precise complex multiplex edits of cell lines, while decreasing the potential of unintended consequences.

Achieving CAR-T cell generation in a single intervention using a multiplex base editing system
In this poster, we highlight an example configuration of the Pin-point technology for the streamlined generation of allogeneic CAR-T cells and hypoimmunogenic iPSCs.

Increasing the targeting scope and precision of next-generation gene editing technology
In this application note, we demonstrate the Pin-point™ base editing system as a novel nucleaseagnostic modular platform for increasing the targeting scope and precision of next-generation gene editing technology.

Cellometer X2 fluorescent cell viability counter: A rapid method for Candida albicans culture sample stability determination.
Application Note using the Cellometer X2 fluorescent cell viability counter to determine Candida albicans culture sample stability.

Empowering T cell therapies: the strategic use of LentiBOOST in CAR T and TCR modalities
This literature review demonstrates how the LentiBOOST™ transduction enhancer can be applied to CAR T and TCR modalities.

Image-Based CAR-T Cell Assays for Apoptosis and CAR Expression Monitoring
This poster introduces a new image-based method to monitor CAR expression and apoptosis in CAR-T cells, offering insights into cell viability post-gene delivery.

Optimization of Modular Pin-point™ Base Editing with Type V CRISPR-Cas
This poster details advancements in the Pin-point™ base editing platform, focusing on modularity and efficiency improvements with Type V CRISPR-Cas effector applications in gene therapy.

Enhanced iPSC Editing with Minimal p53 Activation via Pin-point™
Focused on improving iPSC editing, this poster discusses reduced p53 pathway activation with Pin-point™ cytidine base editing, enhancing cell viability and therapeutic outcomes.


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