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Brochure
The Pin-point™ platform: A novel modular base editing system
This presentation provides an overview of the Pin-point base editing platform by describing its key benefits, how it works, and supporting data.
Whitepaper
Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.
Application Note
Optimization of complement-dependent cytotoxicity assay on OncoSignature cell lines
This application note provides insight into how our complement-dependent cytotoxicity assay can help drug screening efforts by leveraging our semi-automated screening platform and OncoSignature™ cell panel.
Guide
Immune cell compound screening compendium
This application compedium provides an overview of four immune cell compound screening applications using ImmuSignature™ assays.
Whitepaper
CRISPR-derived base editing technology: The what, the how, and the why
This white paper provides a comprehensive guide to base editing, including what it is, how it works and applications.
Scientific Poster
One-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform
Discover one-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform.
Scientific Poster
Base Editing of Human Hematopoietic Stem and Progenitor Cells with the Base Editing of Human Hematopoietic Stem and Progenitor Cells with the Pin-point™ platform
Learn why the Pin-point™ base editing platform is a valuable tool for the generation of advanced cell therapies using sensitive cell types.
Flyer
LentiBOOST transduction enhancer
This flyer provides an overview of the LentiBOOST transduction enhancer technology.
Webinar
Advancing Gene Editing Efficiency and Precision with the Pin-point™ Base Editing Platform
This webinar discusses how the Pin-point™ base editing platform can achieve more efficient and precise complex multiplex edits of cell lines, while decreasing the potential of unintended consequences.
Scientific Poster
Achieving CAR-T cell generation in a single intervention using a multiplex base editing system
In this poster, we highlight an example configuration of the Pin-point technology for the streamlined generation of allogeneic CAR-T cells and hypoimmunogenic iPSCs.
Application Note
Increasing the targeting scope and precision of next-generation gene editing technology
In this application note, we demonstrate the Pin-point™ base editing system as a novel nucleaseagnostic modular platform for increasing the targeting scope and precision of next-generation gene editing technology.
Scientific Poster
Development and validation of customized guide RNA design and efficiency prediction tools for the Pin-point base editing platform
This scientific poster describes the development and validation of customized guide RNA design and efficiency prediction tools for the Pin-point base editing platform.
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