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Poster Icon   Scientific Poster
Development and validation of customized guide RNA design and efficiency prediction tools for the Pin-point base editing platform
This scientific poster describes the development and validation of customized guide RNA design and efficiency prediction tools for the Pin-point base editing platform.
Application Note Icon   Application Note
Complex genome engineering with the Pin-point base editing system
This application note describes how Pin-point base editing platform can be applied to complex gene editing, even in sensitive cell types.
Whitepaper Icon   Whitepaper
Finding the right technology for your genome engineering project
Learn about how to select the right technology for your genome engineering project in this white paper.
Whitepaper Icon   Whitepaper
Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.
Application Note Icon   Application Note
Optimization of complement-dependent cytotoxicity assay on OncoSignature cell lines
This application note provides insight into how our complement-dependent cytotoxicity assay can help drug screening efforts by leveraging our semi-automated screening platform and OncoSignature™ cell panel.
Guide Icon   Guide
Immune cell compound screening compendium
This application compedium provides an overview of four immune cell compound screening applications using ImmuSignature™ assays.
Whitepaper Icon   Whitepaper
CRISPR-derived base editing technology: The what, the how, and the why
This white paper provides a comprehensive guide to base editing, including what it is, how it works and applications.
Poster Icon   Scientific Poster
One-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform
Discover one-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform.
Poster Icon   Scientific Poster
Base Editing of Human Hematopoietic Stem and Progenitor Cells with the Base Editing of Human Hematopoietic Stem and Progenitor Cells with the Pin-point™ platform
Learn why the Pin-point™ base editing platform is a valuable tool for the generation of advanced cell therapies using sensitive cell types.
Poster Icon   Scientific Poster
Optimization of Modular Pin-point™ Base Editing with Type V CRISPR-Cas
This poster details advancements in the Pin-point™ base editing platform, focusing on modularity and efficiency improvements with Type V CRISPR-Cas effector applications in gene therapy.
Poster Icon   Scientific Poster
Enhanced iPSC Editing with Minimal p53 Activation via Pin-point™
Focused on improving iPSC editing, this poster discusses reduced p53 pathway activation with Pin-point™ cytidine base editing, enhancing cell viability and therapeutic outcomes.
Poster Icon   Scientific Poster
Custom gRNA Design and Efficiency Prediction in Pin-point™ Editing
This poster discusses the development of custom guide RNA (gRNA) design tools and efficiency prediction models, enhancing Pin-point™ base editing accuracy in gene therapy applications.
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