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Scientific Poster
Optimization of Modular Pin-point™ Base Editing with Type V CRISPR-Cas
This poster details advancements in the Pin-point™ base editing platform, focusing on modularity and efficiency improvements with Type V CRISPR-Cas effector applications in gene therapy.
Scientific Poster
Enhanced iPSC Editing with Minimal p53 Activation via Pin-point™
Focused on improving iPSC editing, this poster discusses reduced p53 pathway activation with Pin-point™ cytidine base editing, enhancing cell viability and therapeutic outcomes.
Scientific Poster
Custom gRNA Design and Efficiency Prediction in Pin-point™ Editing
This poster discusses the development of custom guide RNA (gRNA) design tools and efficiency prediction models, enhancing Pin-point™ base editing accuracy in gene therapy applications.
Scientific Poster
Advancements in Pin-point™ Base Editing for Targeted Gene Therapy
This poster showcases the latest improvements in the Pin-point™ base editing platform, emphasizing applications in targeted gene therapy for enhanced therapeutic outcomes.
Scientific Poster
Multi-Omic Analysis of Immune Cells Using Pin-point™ Base Editing
Presenting multi-omic analysis techniques for immune cells edited with Pin-point™, this poster uncovers insights into cell engineering outcomes in CAR-T therapies.
Scientific Poster
Development of a High-Efficiency RNA-Guided Base Editing System
Presenting a high-efficiency RNA-guided base editing platform, this poster explores increased precision in gene editing applications, suitable for cell therapy advancements.
Scientific Papers
Modular Pin-point™ Base Editing for Multi-Target Efficiency
Detailing the modular capabilities of the Pin-point™ base editing platform, this poster examines its role in multi-gene targeting for streamlined cell therapy applications.
Scientific Poster
SMARTvector™ Multiplex shRNA for Enhanced Cell Therapy Safety
Explore the SMARTvector™ multiplex shRNA platform for safe, multi-target gene knockdown in cell therapy applications, offering new levels of therapeutic control and safety.
Literature - Publication Review
A breakthrough aptamer-mediated base editing platform for simultaneous knock-in and multiple gene knockout
This literature review delves into an application of gene editing that achieves simultaneous knock-in and multiple gene knockout.
Webinar
Advancing Gene Editing Efficiency and Precision with the Pin-point™ Base Editing Platform
This webinar discusses how the Pin-point™ base editing platform can achieve more efficient and precise complex multiplex edits of cell lines, while decreasing the potential of unintended consequences.
Scientific Poster
Achieving CAR-T cell generation in a single intervention using a multiplex base editing system
In this poster, we highlight an example configuration of the Pin-point technology for the streamlined generation of allogeneic CAR-T cells and hypoimmunogenic iPSCs.
Application Note
Increasing the targeting scope and precision of next-generation gene editing technology
In this application note, we demonstrate the Pin-point™ base editing system as a novel nucleaseagnostic modular platform for increasing the targeting scope and precision of next-generation gene editing technology.
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