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Scientific Poster
Achieving CAR-T cell generation in a single intervention using a multiplex base editing system
In this poster, we highlight an example configuration of the Pin-point technology for the streamlined generation of allogeneic CAR-T cells and hypoimmunogenic iPSCs.
Application Note
Increasing the targeting scope and precision of next-generation gene editing technology
In this application note, we demonstrate the Pin-point™ base editing system as a novel nucleaseagnostic modular platform for increasing the targeting scope and precision of next-generation gene editing technology.
Scientific Poster
Development and validation of customized guide RNA design and efficiency prediction tools for the Pin-point base editing platform
This scientific poster describes the development and validation of customized guide RNA design and efficiency prediction tools for the Pin-point base editing platform.
Application Note
Complex genome engineering with the Pin-point base editing system
This application note describes how Pin-point base editing platform can be applied to complex gene editing, even in sensitive cell types.
Whitepaper
Finding the right technology for your genome engineering project
Learn about how to select the right technology for your genome engineering project in this white paper.
Application Note
Cellometer X2 fluorescent cell viability counter: A rapid method for Candida albicans culture sample stability determination.
Application Note using the Cellometer X2 fluorescent cell viability counter to determine Candida albicans culture sample stability.
Literature - Publication Review
A breakthrough aptamer-mediated base editing platform for simultaneous knock-in and multiple gene knockout
This literature review delves into an application of gene editing that achieves simultaneous knock-in and multiple gene knockout.
Literature - Publication Review
Empowering T cell therapies: the strategic use of LentiBOOST in CAR T and TCR modalities
This literature review demonstrates how the LentiBOOST™ transduction enhancer can be applied to CAR T and TCR modalities.
Product Note
PhenoVue Fluor - Donkey anti-Mouse IgG (H+L) Antibody Conjugates
Product information sheet for PhenoVue Fluor - Donkey anti-mouse IgG (H&L)antibody conjugates. View validation data, product information, protocols, and more.
Scientific Poster
Image-Based CAR-T Cell Assays for Apoptosis and CAR Expression Monitoring
This poster introduces a new image-based method to monitor CAR expression and apoptosis in CAR-T cells, offering insights into cell viability post-gene delivery.
Scientific Poster
Optimization of Modular Pin-point™ Base Editing with Type V CRISPR-Cas
This poster details advancements in the Pin-point™ base editing platform, focusing on modularity and efficiency improvements with Type V CRISPR-Cas effector applications in gene therapy.
Scientific Poster
Enhanced iPSC Editing with Minimal p53 Activation via Pin-point™
Focused on improving iPSC editing, this poster discusses reduced p53 pathway activation with Pin-point™ cytidine base editing, enhancing cell viability and therapeutic outcomes.
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