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Application Note
Imaging bile canaliculi in 3D liver microtissues
Here, we describe a 3D HCS assay to study hepatobiliary transporter function in InSphero human liver microtissues using the Opera Phenix™ HCS system.
Whitepaper
Targeting leishmaniasis with an entamoeba molecule
An immune-therapeutic approach to leishmaniasis treatment by targeting leishmaniasis with an entamoeba molecule.
Whitepaper
Assessing juvenile batten disease on Brain Development in In Vitro 3D organoid models
Assessing Juvenile Neuronal ceroid lipofuscinosis (JNCL) on brain development in Vitro 3D organoid Models.
Whitepaper
High-Throughput Approaches to Overcome Antimicrobial Resistance - Part 2
The use of machine learning algorithms to predict how an organism is going to behave in response to an antimicrobial.
Whitepaper
COVID-19 therapeutics: demand, challenges, and the future
Whitepaper provides insights into why developing effective COVID-19 treatments plays a significant role in pandemic control and explores therapeutic approaches pursued.
Infographic
Diabetes research pathways to prevention and therapies
Diabetes is a complex disease affecting nearly every major bodily organ and impacting the lives of millions of people worldwide. That's why researchers are devoted to developing effective treatment strategies.
Whitepaper
Postbiotics: a paradigm shift in microbiome research
Investigating the impact of molecules produced by microbiota metabolism, known as postbiotics, on the human host
Infographic
Deeper insights from your 3D cell model imaging
Infographic describing tools and strategies to get the most out of your 3D cell model imaging and analysis workflows.
Technical Note
Nuclei segmentation on brightfield images using a pre-trained Artificial Intelligence (AI) model
Technical note describing the use of Phenologic.AI software module, for Signals Image Artist and Harmony image analysis software, for nuclei segmentation of brightfield images.
Application Note
Orthogonal validation of CRISPRCas9 and siRNA generated phenotypes using cell painting
Investigate cell cycle regulation through AURKB, GMNN, and PLK1 proteins. Learn how CRISPR-Cas9 and siRNA techniques, combined with high-content imaging on the Opera Phenix™ Plus, reveal their roles in cell division and genomic stability.
Application Note
CDK signaling: Investigate CDK4/6 inhibition in breast cancer cell lines with HTRF immunoassays
Learn how to analyze the inhibition of CDK4 and CDK9 in breast cancer using no-wash immunoassays.
Application Note
HTRF platform for anticancer drug discovery: from 2D and 3D cell cultures to xenograft models
Learn how to analyze cell signaling pathways on in vitro and in vivo sample types routinely used in the anticancer drug discovery process.
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