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Application Note
CRISPRsc: Pooled CRISPR screening with single-cell transcriptome resolution
This application note describes a pooled CRISPR screen with single-cell transcriptome resolution to link gene expression signature with drug response.
Application Note
CRISPR-Cas9 screening for target identification
Explore the power of whole-genome CRISPR-Cas9 screening in this application note.
Application Note
CRISPRa: Transcriptional upregulation screening with genome-wide CRISPR activation
This application note demonstrates transcriptional upregulation screening with genome-wide CRISPR activation.
Application Note
The dual screen: Parallel genome-wide CRISPRi and CRISPRa screening
Discover the advantages of a dual screen using CRISPRi and CRISPRa screening in parallel in this application note.
Application Note
CRISPRi: Transcriptional repression screening with genome-wide CRISPR interference
This application note demonstrates transcriptional regression screening with a novel whole-genome CRISPRi platform.
Flyer
Preclinical services reading list
Selected publications that utilizes Revvity’s Preclinical Services to enhance scientific research and progress drug discovery.
Application Note
Target essentiality assay
This application note demonstrates Revvity’s target essentiality assay which indicates whether or not a specific gene is essential for survival and/or proliferation in a given cell line.
Whitepaper
How CRISPR-based functional genomics is transforming drug discovery
Exploring how functional genomics is used in preclinical drug discovery with target identification, drug response mechanisms, and in vivo tumor biology.
Brochure
Cell engineering and screening services ebook
Explore Revvity's preclinical services for cell engineering and screening in our ebook.
Technical Note
A scalable and reproducible workflow for high-content analysis of cytotoxic effects in RASTRUM 3D cell cultures
Explore our Technical Note on a scalable workflow for high-content cytotoxicity analysis in 3D cell cultures. Discover reproducible 3D model creation, tailored microenvironment techniques, and enhanced imaging methods for accurate drug testing.
Whitepaper
Gene editing of primary immune cells to aid next-generation cellular immunotherapies
Researchers have successfully deployed CRISPRa/i in primary human T cells, offering critical insights into the pathways required for cytokine regulation.
Infographic
Functional genomic screening in drug discovery
In this infographic we present two screening approaches, pooled and array, summarize advantages, read-out methods and available products and technologies.
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