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Application Note

CRISPRsc: Pooled CRISPR screening with single-cell transcriptome resolution

This application note describes a pooled CRISPR screen with single-cell transcriptome resolution to link gene expression signature with drug response.

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Application Note

CRISPR-Cas9 screening for target identification

Explore the power of whole-genome CRISPR-Cas9 screening in this application note.

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Application Note

CRISPRa: Transcriptional upregulation screening with genome-wide CRISPR activation

This application note demonstrates transcriptional upregulation screening with genome-wide CRISPR activation.

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Application Note

The dual screen: Parallel genome-wide CRISPRi and CRISPRa screening

Discover the advantages of a dual screen using CRISPRi and CRISPRa screening in parallel in this application note.

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Application Note

CRISPRi: Transcriptional repression screening with genome-wide CRISPR interference

This application note demonstrates transcriptional regression screening with a novel whole-genome CRISPRi platform.

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Flyer

Preclinical services reading list

Selected publications that utilizes Revvity’s Preclinical Services to enhance scientific research and progress drug discovery.

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Application Note

Target essentiality assay

This application note demonstrates Revvity’s target essentiality assay which indicates whether or not a specific gene is essential for survival and/or proliferation in a given cell line.

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Whitepaper

How CRISPR-based functional genomics is transforming drug discovery

Exploring how functional genomics is used in preclinical drug discovery with target identification, drug response mechanisms, and in vivo tumor biology.

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Whitepaper

A guide to In Vitro Transcription (IVT) and the importance of dsRNA detection

Discover the essentials of In Vitro Transcription (IVT) and the importance of dsRNA detection in RNA-based therapeutics. This white paper covers IVT processes, applications, and advanced dsRNA detection methods to ensure the quality and safety of biotherapeutic products.

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Brochure